While Irlen Syndrome seems to run in families and many studies have noted hereditary markers, it is not purely genetic. The cause of Irlen Syndrome seems to be a problem in the visual pathway between the eye and the brain, a problem that causes visual processing to fail to synchronize, which leads to perceptual dysfunction.
Researchers discovered another interesting correlation when delving into Irlen Syndrome. As stated above, approximately 14% of the general population may have Irlen Syndrome. That number jumps up significantly for people with a learning or reading difficulty. Nearly half of people in this category also have Irlen Syndrome, along with about 1/3 of people on the autism spectrum and 1/3 of those with a concentration or attention problem such as ADHD.